The reduced expression of endogenous duplications (REED) in the maize R gene family is mediated by DNA methylation.

@article{Ronchi1995TheRE,
  title={The reduced expression of endogenous duplications (REED) in the maize R gene family is mediated by DNA methylation.},
  author={Angela Ronchi and Katia Petroni and Chiara Tonelli},
  journal={The EMBO journal},
  year={1995},
  volume={14 21},
  pages={5318-28}
}
The duplicated R and Sn genes regulate the maize anthocyanin biosynthetic pathway and encode tissue-specific products that are homologous to helix-loop-helix transcriptional activators. As a consequence of their coupling in the genome, Sn is partially silenced. Genomic restriction analysis failed to reveal gross structural DNA alterations between the strong original phenotype and the weak derivatives. However, the differences in pigmentation were inversely correlated with differences in the… CONTINUE READING
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