The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease.

@article{PaceAsciak1995TheRW,
  title={The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease.},
  author={Cecil R. Pace-Asciak and S E Hahn and Eleftherios P Diamandis and George Soleas and David M. Goldberg},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={1995},
  volume={235 2},
  pages={207-19}
}
A number of lines of evidence suggest that red wine may be more effective than other alcoholic beverages in decreasing the risk of coronary heart disease (CHD) mortality. This protection over and above that due to ethanol itself may be explained by phenolic components with which red wines are richly endowed. We have studied the effects of the trihydroxy stilbene trans-resveratrol on human platelet aggregation and on the synthesis of three eicosanoids from arachidonate by platelets, i.e… CONTINUE READING
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