The red blood cell participates in regulation of the circulation by producing and releasing epoxyeicosatrienoic acids.

@article{Jiang2012TheRB,
  title={The red blood cell participates in regulation of the circulation by producing and releasing epoxyeicosatrienoic acids.},
  author={Houli Jiang and G. D. Anderson and J C Mcgiff},
  journal={Prostaglandins & other lipid mediators},
  year={2012},
  volume={98 3-4},
  pages={91-3}
}
Red blood cells (RBCs) have an important function in regulation of the circulation by producing and releasing epoxyeicosatrienoic acids (EETs) in response to a low O₂ environment such as encountered in the cardiac microcirculation during exercise. RBCs, in their role as sensors of low pO₂, release ATP and critical lipid mediators, the EETs. Both cis- and trans-EETs are synthesized and stored in RBCs and are hydrolyzed by soluble epoxide hydrolases (sEH). The trans-EETs differ from cis-EETs in… CONTINUE READING

References

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Hydrolysis of cis- and trans-epoxyeicosatrienoic acids by rat red blood cells.

The Journal of pharmacology and experimental therapeutics • 2008

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