[The recurrence of duodenal ulcer in patients undergoing treatment with ranitidine and placebo. A multicenter study].

Abstract

This randomised, double-blind multicenter study was conducted in order to evaluate the long-term effect (one year) of 150 mg ranitidine vs placebo in 51 patients with healed duodenal ulcer. Seventeen patients had ulcer recurrence at the end of follow-up, one among the 24 patients that received ranitidine and 16 among the 27 patients that received placebo (p = 0.00009). No side effects was detected. Our results support the usefulness of a one-year maintenance therapy with 150 mg ranitidine.

Cite this paper

@article{Villalobos1991TheRO, title={[The recurrence of duodenal ulcer in patients undergoing treatment with ranitidine and placebo. A multicenter study].}, author={Joe J Villalobos and Antonella Nava and Joe Elizondo and Sabrina Gallo and Cesar Ivan Guerrero and Franklin Vargas and Ariel Barrera and Federico Centeno and Ettore Marin and Florencia Pe{\~n}a}, journal={Revista de gastroenterología de México}, year={1991}, volume={56 2}, pages={65-9} }