The recovery of hormone responsiveness in desensitized neonatal rat calvariae.


Two issues were studied: the loss of hormone responsiveness during culture of neonatal rat calvariae under standard culture conditions and the recovery of hormone responsiveness in calvariae previously desensitized with PTH (2.5 U/ml), prostaglandin E2 (PGE2; 1 or 2.5 micrograms/ml), or salmon calcitonin (sCT; 100 mU/ml). Both of these issues were studied… (More)


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