The reconstruction of a three-dimensional structure from projections and its application to electron microscopy

@article{Crowther1970TheRO,
title={The reconstruction of a three-dimensional structure from projections and its application to electron microscopy},
author={R. A. Crowther and D. Derosier and A. Klug},
journal={Proceedings of the Royal Society of London. A. Mathematical and Physical Sciences},
year={1970},
volume={317},
pages={319 - 340}
}

Proceedings of the Royal Society of London. A. Mathematical and Physical Sciences

A transmission electron micrograph is essentially a projection of the specimen in the direction of view. In order to reconstruct a three-dimensional image of the specimen, it is necessary to be able to combine data from a number of different views. A formal solution of this problem is given in terms of Fourier transforms. Its realization requires data reduction and interpolation. The final solution is given by a least squares approach, which also indicates how many views must be included to… CONTINUE READING