The reconstruction of a three-dimensional structure from projections and its application to electron microscopy

@article{Crowther1970TheRO,
  title={The reconstruction of a three-dimensional structure from projections and its application to electron microscopy},
  author={R. A. Crowther and D. Derosier and A. Klug},
  journal={Proceedings of the Royal Society of London. A. Mathematical and Physical Sciences},
  year={1970},
  volume={317},
  pages={319 - 340}
}
  • R. A. Crowther, D. Derosier, A. Klug
  • Published 1970
  • Mathematics
  • Proceedings of the Royal Society of London. A. Mathematical and Physical Sciences
  • A transmission electron micrograph is essentially a projection of the specimen in the direction of view. In order to reconstruct a three-dimensional image of the specimen, it is necessary to be able to combine data from a number of different views. A formal solution of this problem is given in terms of Fourier transforms. Its realization requires data reduction and interpolation. The final solution is given by a least squares approach, which also indicates how many views must be included to… CONTINUE READING
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