The receptors and coding logic for bitter taste

@article{Mueller2005TheRA,
  title={The receptors and coding logic for bitter taste},
  author={Ken L. Mueller and Mark A. Hoon and Isolde Erlenbach and Jayaram Chandrashekar and Charles S. Zuker and Nicholas J. P. Ryba},
  journal={Nature},
  year={2005},
  volume={434},
  pages={225-229}
}
The sense of taste provides animals with valuable information about the nature and quality of food. Bitter taste detection functions as an important sensory input to warn against the ingestion of toxic and noxious substances. T2Rs are a family of approximately 30 highly divergent G-protein-coupled receptors (GPCRs) that are selectively expressed in the tongue and palate epithelium and are implicated in bitter taste sensing. Here we demonstrate, using a combination of genetic, behavioural and… 

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