The receptor tyrosine kinase Tie1 is expressed and activated in epithelial tumour cell lines.

Abstract

The receptor tyrosine kinase Tie1 is expressed primarily in vascular endothelial cells. The receptor has also been detected in epithelial tumours in breast, thyroid and gastric cancers and in tumour cell lines where it appears as a 45 kDa truncated receptor fragment. In this study, we show that in addition to truncated Tie1, breast and colon tumour cell… (More)

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Cite this paper

@article{Rees2007TheRT, title={The receptor tyrosine kinase Tie1 is expressed and activated in epithelial tumour cell lines.}, author={Kathryn A Rees and Harprit Singh and Nicholas P. J. Brindle}, journal={International journal of oncology}, year={2007}, volume={31 4}, pages={893-7} }