The receptor tyrosine kinase Axl in cancer: biological functions and therapeutic implications.

Abstract

The receptor tyrosine kinase Axl has been implicated in the malignancy of different types of cancer. Emerging evidence of Axl upregulation in numerous cancers, as well as reports demonstrating that its inhibition blocks tumor formation in animal models, highlight the importance of Axl as a new potential therapeutic target. Furthermore, recent data… (More)
DOI: 10.1002/ijc.28246

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