The receptor for advanced glycation end products and its ligands: a new inflammatory pathway in lung disease?

@article{Morbini2006TheRF,
  title={The receptor for advanced glycation end products and its ligands: a new inflammatory pathway in lung disease?},
  author={Patrizia Morbini and Chiara Villa and Ilaria Campo and Michele Zorzetto and Simona Inghilleri and Maurizio Luisetti},
  journal={Modern Pathology},
  year={2006},
  volume={19},
  pages={1437-1445}
}
The binding of the receptor for advanced glycation end products (RAGE) with its ligands begins a sustained period of cellular activation and inflammatory signal amplification in different tissues and diseases. This binding could represent an as yet uninvestigated pathway of inflammatory reaction in the lung, where the presence of the receptor has been largely documented and advanced glycation end products (AGEs) are produced by nonenzymatic glycation and oxidation of proteins and lipids, driven… CONTINUE READING
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