The recent origins of introns.

  title={The recent origins of introns.},
  author={Jeffrey D. Palmer and John M. Logsdon},
  journal={Current opinion in genetics & development},
  volume={1 4},
Accumulating evidence that introns are highly restricted in their phylogenetic distribution strongly supports the view that introns were inserted late in eukaryotic evolution into preformed genes and, hence, that exon-shuffling played no role in the assembly of primordial genes. Potential mechanisms of intron insertion and the possible evolution of nuclear introns and their splicing machinery from self-splicing group II introns are also discussed. 

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Introns: evolution and function.

Current opinion in genetics & development • 1994
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