The rebirth of culture in microbiology through the example of culturomics to study human gut microbiota.

Abstract

Bacterial culture was the first method used to describe the human microbiota, but this method is considered outdated by many researchers. Metagenomics studies have since been applied to clinical microbiology; however, a "dark matter" of prokaryotes, which corresponds to a hole in our knowledge and includes minority bacterial populations, is not elucidated… (More)
DOI: 10.1128/CMR.00014-14

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