The re-organization of functional brain networks in pharmaco-resistant epileptic patients who respond to VNS.

@article{Fraschini2014TheRO,
  title={The re-organization of functional brain networks in pharmaco-resistant epileptic patients who respond to VNS.},
  author={Matteo Fraschini and Matteo Demuru and Monica Puligheddu and Simona Floridia and Lorenzo Polizzi and Alberto Maleci and Marco Bortolato and Arjan Hillebrand and Francesco Marrosu},
  journal={Neuroscience letters},
  year={2014},
  volume={580},
  pages={153-7}
}
Vagal nerve stimulation (VNS) is a therapeutic add-on treatment for patients with pharmaco-resistant epilepsy. The mechanism of action is still largely unknown. Previous studies have shown that brain network topology during the inter-ictal period in epileptic patients deviates from normal configuration. In the present paper, we investigate the relationship between clinical improvement induced by VNS and alterations in brain network topology. We hypothesize that, as a consequence of the VNS add… CONTINUE READING
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