The rat probasin gene promoter directs hormonally and developmentally regulated expression of a heterologous gene specifically to the prostate in transgenic mice.

@article{Greenberg1994TheRP,
  title={The rat probasin gene promoter directs hormonally and developmentally regulated expression of a heterologous gene specifically to the prostate in transgenic mice.},
  author={Norman M. Greenberg and Francesco J. Demayo and Patricia C. Sheppard and Roberto J. Barrios and Russell M. Lebovitz and Milton J. Finegold and Roxani Angelopoulou and Janice G. Dodd and Mary Lynn Duckworth and Jeffrey M. Rosen},
  journal={Molecular endocrinology},
  year={1994},
  volume={8 2},
  pages={230-9}
}
An expression cassette carrying 426 basepairs of the rat probasin (PB) gene promoter and 28 basepairs of 5'-untranslated region is sufficient to target the expression of the bacterial chloramphenicol acetyltransferase (CAT) gene specifically to the prostate in transgenic mice. The PB-CAT transgene was expressed in three of five (60%) independent lines of… CONTINUE READING