The rat fructose-1,6-bisphosphatase gene. Structure and regulation of expression.

@article{ElMaghrabi1991TheRF,
  title={The rat fructose-1,6-bisphosphatase gene. Structure and regulation of expression.},
  author={M. Raafat El-Maghrabi and Alex J. Lange and Lutz K{\"u}mmel and Simon J. Pilkis},
  journal={The Journal of biological chemistry},
  year={1991},
  volume={266 4},
  pages={
          2115-20
        }
}
The gene encoding rat fructose-1,6-bisphosphatase was isolated from a rat genomic Charon 4A library by screening with a cDNA to the rat liver enzyme. Southern blotting of rat genomic DNA showed that there is a single copy of the fructose-1,6-bisphosphatase gene. It extends over 23 kilobases and is composed of seven exons and six introns that range in size from 93 to 267 base pairs and from 1,400 to 11,300 base pairs, respectively. The intron/exon boundary sequences conform to consensus acceptor… Expand
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