• Biology, Medicine
  • Published in
    Investigative ophthalmology…
    1987

The rat electroretinogram in combined zinc and vitamin A deficiency.

@article{Kraft1987TheRE,
  title={The rat electroretinogram in combined zinc and vitamin A deficiency.},
  author={Stephen P. Kraft and John Alexander Parker and Y. Matuk and Akkinapally Venketeshwer Rao},
  journal={Investigative ophthalmology & visual science},
  year={1987},
  volume={28 6},
  pages={
          975-84
        }
}
To assess the relative importance and interdependence of zinc and vitamin A in retinal function, a group of 36 male Wistar rats were raised in dim illumination and deprived of both zinc and vitamin A (Z-A-) for 90 days (Phase I) until they lost weight and showed signs of both vitamin A and zinc deficiency. Scotopic electroretinograms (ERGs) showed an average 1.5 log unit elevation in light intensity needed to elicit a 200 microV b-wave (criterion intensity) as compared to a control-pair-fed… CONTINUE READING

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