The rat distal colon P-ATPase alpha subunit encodes a ouabain-sensitive H+, K+-ATPase.

@article{Cougnon1996TheRD,
  title={The rat distal colon P-ATPase alpha subunit encodes a ouabain-sensitive H+, K+-ATPase.},
  author={Marc Cougnon and Gabrielle Planelles and M S Crowson and Gary E. Shull and Bernard C Rossier and Fr{\'e}d{\'e}ric Jaisser},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 13},
  pages={7277-80}
}
The functional properties and the pharmacological profile of the recently cloned cDNA colonic P-ATPase alpha subunit (Crowson, M.S., and Shull, G.E. (1992) J. Biol. Chem. 267, 13740-13748) were investigated by using the Xenopus oocyte expression system. Xenopus oocytes were injected with alpha subunit cRNAs from Bufo marinus bladder or rat distal colon and/or with beta subunit cRNA from B. marinus bladder. Two days after injection, K+ uptake was measured by using 86 Rb+ as a K+ surrogate, and… CONTINUE READING
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