The rat H+/K(+)-ATPase beta subunit gene and recognition of its control region by gastric DNA binding protein.

@article{Maeda1991TheRH,
  title={The rat H+/K(+)-ATPase beta subunit gene and recognition of its control region by gastric DNA binding protein.},
  author={Masahide Maeda and Ko-ichi Oshiman and Shigehiko Tamura and Shunji Kaya and Saleh T. Mahmood and M A Reuben and Linda S. Lasater and George b. Sachs and Masamitsu Futai},
  journal={The Journal of biological chemistry},
  year={1991},
  volume={266 32},
  pages={
          21584-8
        }
}
The rat gastric H+/K(+)-ATPase beta subunit gene was cloned, and its nucleotide sequence was determined. The coding region is separated by 6 introns, whereas the related human Na+/K(+)-ATPase beta subunit gene was shown to have 5 introns (Lane, L.K., Shull, M.M., Whitmer, K.R., and Lingrel, J.B. (1989) Genomics 5, 445-453). The positions of introns 1, 2, and 5 of the two genes were the same. The similarities in intron/exon organizations and primary structures (30-40% identical residues) suggest… CONTINUE READING

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