The range and clinical impact of cognitive impairment in French patients with ALS: a cross-sectional study of neuropsychological test performance.

@article{Gordon2011TheRA,
  title={The range and clinical impact of cognitive impairment in French patients with ALS: a cross-sectional study of neuropsychological test performance.},
  author={Paul H. Gordon and Daniel Delgadillo and Ambre Piquard and Gaelle Bruneteau and P-F Pradat and François Salachas and Christine Payan and Vincent Meininger and Lucette Lacomblez},
  journal={Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases},
  year={2011},
  volume={12 5},
  pages={372-8}
}
Our objective was to assess the spectrum and clinical associations of cognitive impairment in French patients with ALS, and determine the effect of cognitive impairment on survival in this population. One hundred and thirty-one patients were enrolled in a cross-sectional cohort study of neuropsychological test performance. ANOVA and χ(2) tests assessed differences in clinical characteristics between impaired and unimpaired patients; multiple regression determined which features contributed most… CONTINUE READING