The quantity of nucleolar proteins nucleolin and protein B23 is related to cell doubling time in human cancer cells.

@article{Derenzini1995TheQO,
  title={The quantity of nucleolar proteins nucleolin and protein B23 is related to cell doubling time in human cancer cells.},
  author={Massimo Derenzini and Valentina Sirri and Davide Trer{\'e} and Robert L. Ochs},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1995},
  volume={73 4},
  pages={
          497-502
        }
}
BACKGROUND The quantity of the silver-stained nucleolar proteins (AgNOR proteins) measured in situ in cytohistologic preparations is related to the rapidity of cell proliferation. The term "AgNOR proteins" comprises several proteins. The relationship between the individual AgNOR protein amount and cell proliferating activity is not yet known. We studied the quantitative distribution of the individual AgNOR proteins, with specific attention to the two major AgNOR proteins, nucleolin and protein… CONTINUE READING

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