The quantitation of a native chondroitin sulfate epitope in synovial fluid lavages and articular cartilage from canine experimental osteoarthritis and disuse atrophy.

@article{Ratcliffe1993TheQO,
  title={The quantitation of a native chondroitin sulfate epitope in synovial fluid lavages and articular cartilage from canine experimental osteoarthritis and disuse atrophy.},
  author={Anthony Ratcliffe and Wenda Shurety and Bruce Caterson},
  journal={Arthritis and rheumatism},
  year={1993},
  volume={36 4},
  pages={543-51}
}
OBJECTIVE Previous studies have shown the presence of a native chondroitin sulfate epitope in articular cartilage proteoglycans from canine knee joints with experimental early osteoarthritis (OA), but not in normal cartilage. The objective of this study was to quantitate the native epitope recognized by monoclonal antibody 3-B-3 in synovial fluids and articular cartilage of diseased joints. METHODS An immunoassay with monoclonal antibody 3-B-3, which recognizes a native chondroitin-6-sulfate… CONTINUE READING

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