The puzzle of HIV‐1 subtypes in Africa
@article{Janssens1997ThePO, title={The puzzle of HIV‐1 subtypes in Africa}, author={Wouter Janssens and Anne Buvé and John N. Nkengasong}, journal={AIDS}, year={1997}, volume={11}, pages={705–712} }
HIV has a high degree of genetic variability. While much is known about the differences between HIV-1 and HIV-2 in terms of transmissibility pathogenesis and pattern of spread much remains to be learned about the biological characteristics and epidemic spread of the different HIV-1 strains. Before 1992 HIV-1 strains were classified on the basis of their geographic origin into North American and African variants. However since 1992 the env coding sequence has been used to classify globally…
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