The putative gamma-glutamylcysteine synthetase from Plasmodium falciparum contains large insertions and a variable tandem repeat.

@article{Lersen1999ThePG,
  title={The putative gamma-glutamylcysteine synthetase from Plasmodium falciparum contains large insertions and a variable tandem repeat.},
  author={Kai L{\"u}ersen and Rolf D. Walter and Sylke M{\"u}ller},
  journal={Molecular and biochemical parasitology},
  year={1999},
  volume={98 1},
  pages={131-42}
}
The tripeptide glutathione plays a pivotal role in the maintenance of the thiol redox state of the cell and for the detoxification of reactive oxygen species. Glutathione is synthesized in two consecutive reactions by y-glutamylcysteine synthetase (gamma-GCS) and glutathione synthetase, respectively. The former enzyme represents the rate limiting step of… CONTINUE READING