The psychopathology and treatment of bipolar disorder.

  title={The psychopathology and treatment of bipolar disorder.},
  author={David J. Miklowitz and Sheri L Johnson},
  journal={Annual review of clinical psychology},
In this chapter we review research on the diagnosis, course, etiology, and pharmacological and psychosocial treatment of bipolar disorder (BD). BD is a highly recurrent and severe illness, with high rates of suicidality and functional impairment. The disorder is heritable and appears to share susceptibility genes with schizophrenia. It is characterized by dysregulation in the dopamine and serotonin systems and by pathology in the brain systems involved in regulating emotion. Psychosocial… CONTINUE READING