The pseudorabies immediate early protein stimulates in vitro transcription by facilitating TFIID: promoter interactions.


The pseudorabies virus immediate early (IE) protein, partially purified from infected HeLa cells, stimulated transcription initiation by RNA polymerase II and associated factors in HeLa nuclear extracts. This stimulation was maximal at low template concentrations, where the basal level of transcription was also low. In an analysis of the limitations on… (More)


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