The proximity-labeling technique BioID identifies sorting nexin 6 as a member of the insulin-like growth factor 1 (IGF1)-IGF1 receptor pathway.

@article{Bareja2018ThePT,
  title={The proximity-labeling technique BioID identifies sorting nexin 6 as a member of the insulin-like growth factor 1 (IGF1)-IGF1 receptor pathway.},
  author={Akshay Bareja and Conrad P Hodgkinson and Erik J. Soderblom and Greg M Waitt and Victor J. Dzau},
  journal={The Journal of biological chemistry},
  year={2018},
  volume={293 17},
  pages={6449-6459}
}
The insulin-like growth factor 1 receptor (IGF1R) is a receptor tyrosine kinase with critical roles in various biological processes. Recent results from clinical trials targeting IGF1R indicate that IGF1R signaling pathways are more complex than previously thought. Moreover, it has become increasingly clear that the function of many proteins can be… CONTINUE READING