The prothrombin 20210A allele and the factor V Leiden are associated with venous thrombosis but not with early coronary artery disease.

@article{Vargas1999TheP2,
  title={The prothrombin 20210A allele and the factor V Leiden are associated with venous thrombosis but not with early coronary artery disease.},
  author={Manuel Gil Vargas and I Soto and C R Pinto and M. Fern{\'a}ndez Urgell{\'e}s and Alberto Batalla and Jos{\'e} J. Rodr{\'i}guez-Reguero and Arturo Cortina and Vicente Homero Gonz{\'a}lez {\'A}lvarez and Ernesto Coto},
  journal={Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis},
  year={1999},
  volume={10 1},
  pages={
          39-41
        }
}
This study was performed in order to establish the role of the prothrombin 20210 G/A and factor V Leiden (R506Q) polymorphisms in the susceptibility to develop venous thromboembolism and early coronary artery disease (CAD). These polymorphisms were determined in 82 consecutive patients with venous thromboembolism, 175 male patients with early CAD, and 200 healthy controls from the same Caucasian population (Asturias, Northern Spain). DNA was amplified using polymerase chain reactions and… CONTINUE READING

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Epidemiology of Activated Protein C Resistance and Factor V Leiden Mutation in the Mediterranean Region

  • Mediterranean journal of hematology and infectious diseases
  • 2011
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