The proteomic landscape of triple-negative breast cancer.

@article{Lawrence2015ThePL,
  title={The proteomic landscape of triple-negative breast cancer.},
  author={Robert T. Lawrence and Elizabeth M. Perez and Daniel Guillermo Hern{\'a}ndez and Chris P. Miller and Kelsey M. Haas and Hanna Y. Irie and Su-In Lee and C. Anthony Blau and Judit Vill{\'e}n},
  journal={Cell reports},
  year={2015},
  volume={11 4},
  pages={630-44}
}
Triple-negative breast cancer is a heterogeneous disease characterized by poor clinical outcomes and a shortage of targeted treatment options. To discover molecular features of triple-negative breast cancer, we performed quantitative proteomics analysis of twenty human-derived breast cell lines and four primary breast tumors to a depth of more than 12,000 distinct proteins. We used this data to identify breast cancer subtypes at the protein level and demonstrate the precise quantification of… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 62 references

Similar Papers

Loading similar papers…