The proteomic analysis of mouse choroid plexus secretome reveals a high protein secretion capacity of choroidal epithelial cells.

@article{Thouvenot2006ThePA,
  title={The proteomic analysis of mouse choroid plexus secretome reveals a high protein secretion capacity of choroidal epithelial cells.},
  author={Eric Thouvenot and Mireille Lafon-Cazal and Edith Demettre and Patrick Jouin and J{\"o}el Bockaert and Philippe Marin},
  journal={Proteomics},
  year={2006},
  volume={6 22},
  pages={5941-52}
}
Choroid plexuses (CP) are involved in multiple functions related to their unique architecture and localization at the interface between the blood and cerebrospinal fluid compartments. These include the release by choroidal epithelial cells (CEC) of biologically active molecules, such as polypeptides, which are distributed globally to the brain. Here, we have used a proteomic approach to get an unbiased overview of the proteins that are secreted by primary cultures enriched in epithelial cells… CONTINUE READING

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