The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation

@article{Xia2008ThePO,
  title={The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation},
  author={Dong Dong Xia and Sanya J. Sanderson and Andrew R. Jones and Judith Helena Prieto and John R. Yates and Elizabeth Bromley and F. M. Tomley and Kalpana Lal and Robert E Sinden and Brian P. Brunk and David S. Roos and Jonathan M. Wastling},
  journal={Genome Biology},
  year={2008},
  volume={9},
  pages={R116 - R116}
}
Although the genomes of many of the most important human and animal pathogens have now been sequenced, our understanding of the actual proteins expressed by these genomes and how well they predict protein sequence and expression is still deficient. We have used three complementary approaches (two-dimensional electrophoresis, gel-liquid chromatography linked tandem mass spectrometry and MudPIT) to analyze the proteome of Toxoplasma gondii, a parasite of medical and veterinary significance, and… CONTINUE READING

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