The protein kinase CK2 phosphorylates SNAP190 to negatively regulate SNAPC DNA binding and human U6 transcription by RNA polymerase III.

@article{Gu2007ThePK,
  title={The protein kinase CK2 phosphorylates SNAP190 to negatively regulate SNAPC DNA binding and human U6 transcription by RNA polymerase III.},
  author={Liping Gu and Rhonda D Husain-Ponnampalam and Susanne Hoffmann-Benning and R. William Henry},
  journal={The Journal of biological chemistry},
  year={2007},
  volume={282 38},
  pages={27887-96}
}
Human U6 small nuclear RNA gene transcription by RNA polymerase III requires the general transcription factor SNAP(C), which binds to human small nuclear RNA core promoter elements and nucleates pre-initiation complex assembly with the Brf2-TFIIIB complex. Multiple components in this pathway are phosphorylated by the protein kinase CK2, including the Bdp1… CONTINUE READING