The protein import machinery of the mitochondrial membranes.

  title={The protein import machinery of the mitochondrial membranes.},
  author={Joachim Rassow and Nikolaus Pfanner},
  volume={1 6},
Mitochondria are surrounded by two membranes that contain independent and non-related protein transport machineries. Remarkable progress was recently achieved in elucidating the structure of the outer membrane import channel and in the identification of new components involved in protein traffic across the intermembrane space and the inner membrane. Traditional concepts of protein targeting and sorting had to be revised. Here we briefly summarize the data on the mitochondrial protein import… CONTINUE READING