The protein economy of a cell

  title={The protein economy of a cell},
  author={Ioana A. Visan},
  journal={Nature Immunology},
Post-translational modifications of histone can positively or negatively regulate gene activity, but the full scope of such modifications and their functions are still being determined. In eLife, Schneider and colleagues use mass spectrometry to identify a previously uncharacterized form of histone modification: acetylation of histone H3 at Lys64 (H3K64ac). H3K64ac associates with euchromatin and the transcriptional start sites of active genes and opposes its repressive counterpart, the… CONTINUE READING