The protein acetylome and the regulation of metabolism.

  title={The protein acetylome and the regulation of metabolism.},
  author={Shufan Xing and Yves Poirier},
  journal={Trends in plant science},
  volume={17 7},
Acetyl-coenzyme A (CoA) is a central metabolite involved in numerous anabolic and catabolic pathways, as well as in protein acetylation. Beyond histones, a large number of metabolic enzymes are acetylated in both animal and bacteria, and the protein acetylome is now emerging in plants. Protein acetylation is influenced by the cellular level of both acetyl-CoA and NAD(+), and regulates the activity of several enzymes. Acetyl-CoA is thus ideally placed to act as a key molecule linking the energy… CONTINUE READING
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