The protein MAP-1B links GABAC receptors to the cytoskeleton at retinal synapses

  title={The protein MAP-1B links GABAC receptors to the cytoskeleton at retinal synapses},
  author={Jonathan G Hanley and Peter Koulen and Fiona Kay Bedford and Phillip R. Gordon-Weeks and Stephen J. Moss},
The ionotropic type-A and type-C receptors for the neurotransmitter γ-aminobutyric acid (GABAA and GABAC receptors) are the principal sites of fast synaptic inhibition in the central nervous system, but it is not known how these receptors are localized at GABA-dependent synapses. GABAC receptors, which are composed of ρ-subunits, are expressed almost exclusively inthe retina of adult vertebrates, where they are enriched on bipolar cell axon terminals. Here we show that the microtubule… CONTINUE READING
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