The protein L-isoaspartyl-O-methyltransferase functions in the Caenorhabditis elegans stress response.

Abstract

The efficient use of nutrients is important in development and aging. In this study, we asked if the protein repair methyltransferase has a related or additional role in energy metabolism and stress response in the nematode Caenorhabditis elegans. Worms lacking the pcm-1 gene encoding this enzyme exhibit reduced longevity as SDS-isolated dauer larvae and as… (More)
DOI: 10.1016/j.mad.2008.09.019

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