The protein ICP0 of herpes simplex virus type 1 is targeted to nucleoli of infected cells

@article{Morency2005ThePI,
  title={The protein ICP0 of herpes simplex virus type 1 is targeted to nucleoli of infected cells},
  author={Eric Morency and Yohann Cout{\'e} and Joelle Thomas and Pascale Texier and Patrick Lomonte},
  journal={Archives of Virology},
  year={2005},
  volume={150},
  pages={2387-2395}
}
This study describes the nucleolar localization of the viral protein ICP0 of herpes simplex virus type 1. We show that the RING finger domain of ICP0 is essential for ICP0 to localize in nucleoli of transfected and 4 hour-infected cells. ICP0 forms particular intranucleolar domains that do not correspond to any known nucleolar domains. This distribution was confirmed by immunoblots performed on fractionated infected cells. Quantitative RT-PCR experiments indicated that ICP0 did not increase the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 35 references

Nuclear sequestration of cellular chaperone and proteasomal machinery during herpes simplex virus type 1 infection

  • BurchAD, SK Weller
  • J Virol
  • 2004
1 Excerpt

Similar Papers

Loading similar papers…