The protective role of steroids in ischemia-reperfusion injury of the liver.

@article{Pulitan2008ThePR,
  title={The protective role of steroids in ischemia-reperfusion injury of the liver.},
  author={Carlo Pulitan{\'o} and Luca Antonio Aldrighetti},
  journal={Current pharmaceutical design},
  year={2008},
  volume={14 5},
  pages={
          496-503
        }
}
Liver ischemia-reperfusion injury occurs in a number of clinical settings, including liver surgery, transplantation, and circulatory shock, leading to significant morbidity and mortality. There is a substantial evidence that hepatic ischemia-reperfusion injury results from an intense inflammatory response initiated by oxidative stress in the liver parenchyma during reperfusion. The anti-inflammatory effects of glucocorticosteroids (GCs) have been known for decades and have found extensive… CONTINUE READING
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