The protective role of alpha-lipoic acid on the appearance of fibronectin and laminin in renal tubules following diazinon exposure: an experimental immunohistochemical study.

@article{Anbarkeh2020ThePR,
  title={The protective role of alpha-lipoic acid on the appearance of fibronectin and laminin in renal tubules following diazinon exposure: an experimental immunohistochemical study.},
  author={F. Anbarkeh and M. Nikravesh and M. Jalali and M. Soukhtanloo},
  journal={Toxicology},
  year={2020},
  pages={
          152583
        }
}
Extracellular matrix (ECM) exerts a major role in maintaining the structure and developmental processes of tissues. To form the tubular basement membrane in the kidney, sulfate proteoglycans, collagen, laminin, fibronectin, and other glycoproteins congregate in the ECM. As an insecticide, diazinon (DZN) may alter the proportion of ECM by cholinesterase activity inhibition and oxidative stress. The naturally, alpha-lipoic acid (ALA) plays an effective and therapeutic role in the treatment of… Expand

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