The protective role of Bax Inhibitor-1 against chronic mild stress through the inhibition of monoamine oxidase A

Abstract

The anti-apoptotic protein Bax inhibitor-1 (BI-1) is a regulator of apoptosis linked to endoplasmic reticulum (ER) stress. It has been hypothesized that BI-1 protects against neuron degenerative diseases. In this study, BI-1⁻/⁻ mice showed increased vulnerability to chronic mild stress accompanied by alterations in the size and morphology of the hippocampi… (More)
DOI: 10.1038/srep03398

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