The protective function of human C-reactive protein in mouse models of Streptococcus pneumoniae infection.

@article{Agrawal2008ThePF,
  title={The protective function of human C-reactive protein in mouse models of Streptococcus pneumoniae infection.},
  author={Alok Agrawal and Madathilparambil V. Suresh and Sanjay K. Singh and Donald A. Ferguson},
  journal={Endocrine, metabolic & immune disorders drug targets},
  year={2008},
  volume={8 4},
  pages={231-7}
}
Human C-reactive protein (CRP), injected intravenously into mice or produced inside mice by a human transgene, protects mice from death following administration of lethal numbers of Streptococcus pneumoniae. The protective effect of CRP is due to reduction in the concentration of bacteria in the blood. The exact mechanism of CRP-dependent killing of… CONTINUE READING