The protective effects of preconditioning on cerebral endothelial cells in vitro.

@article{Andjelkovic2003ThePE,
  title={The protective effects of preconditioning on cerebral endothelial cells in vitro.},
  author={Anuska V. Andjelkovic and Svetlana M. Stamatovic and Richard F. Keep},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2003},
  volume={23 11},
  pages={1348-55}
}
Ischemic preconditioning (PC) can markedly reduce ensuing ischemic damage. Although most attention has focused on the neuronal effects of PC, the authors have recently shown that ischemic PC reduces ischemia-induced cerebrovascular damage. In vivo, it is difficult to ascertain whether this is a direct cerebrovascular effect of PC. This study, therefore, examined whether cerebral endothelial cells can be preconditioned in vitro in the absence of other cell types. Experiments were performed on an… CONTINUE READING

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