The protective effects of natural products on blood-brain barrier breakdown.

  title={The protective effects of natural products on blood-brain barrier breakdown.},
  author={Antony Kam and Kong Ming Li and Valentina Razmovski-Naumovski and Srinivas Nammi and K Chan and Yong Li and George Li},
  journal={Current medicinal chemistry},
  volume={19 12},
The blood-brain barrier (BBB) is a protective fence between the central nervous system and the systemic circulation, and is essential for maintaining the normal homeostasis of the central nervous system. BBB breakdown is instigated in many neurological disorders such as Alzheimer's disease and multiple sclerosis. Recent literature has advanced the knowledge on the physiology and pathophysiology of BBB breakdown, including the attribution of detrimental inducers and signalling transduction… CONTINUE READING
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