The protective effects of Ribes diacanthum Pall on cisplatin-induced nephrotoxicity in mice.

@article{Tilyek2016ThePE,
  title={The protective effects of Ribes diacanthum Pall on cisplatin-induced nephrotoxicity in mice.},
  author={Akhtolkhyn Tilyek and Chengzhi Chai and Xiaoli Hou and Baoping Zhou and Chunlei Zhang and Zhengyu Cao and Boyang Yu},
  journal={Journal of ethnopharmacology},
  year={2016},
  volume={178},
  pages={297-306}
}
ETHNOPHARMACOLOGICAL RELEVANCE Ribes diacanthum Pall. (Saxifragaceae), a Mongolian folk medicinal plant, was used to treat urinary system diseases. The present work aims to investigate the protective effects of Ribes diacanthum Pall (RDP) against cisplatin-induced nephrotoxicity. METHODS The renal injury was modeled by intraperitoneal injection of cisplatin for 5 consecutive days (5 mg/kg). Nephroprotection of RDP was investigated by oral administration of RDP aqueous extract at a daily dose… CONTINUE READING

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