The propofol infusion syndrome in infants and children: can we predict the risk?

  • Robin J Bray
  • Published 2002 in Current opinion in anaesthesiology


Propofol has been an immensely successful anaesthetic induction agent but there is an increasing number of reports of serious complications when it has been used as an infusion to provide sedation for prolonged periods. The first reports involved children who died from intractable myocardial failure preceded by a metabolic acidosis, lipaemic plasma, fatty… (More)