The prophylaxis and treatment of heterotopic ossification following lower limb arthroplasty.

  title={The prophylaxis and treatment of heterotopic ossification following lower limb arthroplasty.},
  author={Tim N. Board and A R Karva and R E Board and Anil K. Gambhir and Martyn L Porter},
  journal={The Journal of bone and joint surgery. British volume},
  volume={89 4},
Heterotopic ossification following joint replacement in the lower limb occurs in 3% to 90% of cases. Higher grades of heterotopic ossification can result in significant limitation of function and can negate the benefits of joint replacement. The understanding of the pathophysiology of this condition has improved in recent years. It would appear to be related to a combination of systemic and local factors, including over-expression of bone morphogenetic protein-4. There is currently little… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 57 extracted citations

Prophylaxis of heterotopic ossification – an updated review

Journal of orthopaedic surgery and research • 2009
View 7 Excerpts
Highly Influenced

The effect of late radiotherapy on the progression of heterotopic ossification following total hip arthroplasty

European Journal of Orthopaedic Surgery & Traumatology • 2018
View 3 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 75 references

Evaluation of scrotal and testicular dose when using radiation for heterotopic ossification prophylaxis

HYC Patel, CL Silverman, L Carrascosa
Int J Radiat Oncol Biol Phys 2005;63:340-1 • 2005

Similar Papers

Loading similar papers…