The promoter(s) of the aromatase gene in male testicular cells.

  title={The promoter(s) of the aromatase gene in male testicular cells.},
  author={Serge Carreau and Sonia Bourguiba and Sophie Lambard and Doroth{\'e}e Silandre and Christelle Delalande},
  journal={Reproductive biology},
  volume={4 1},
Aromatase is the terminal enzyme responsible for estrogen biosynthesis in mammals; it is present in various testicular cells including germ cells. The aromatase gene (Cyp19) is unique in humans and its expression is regulated in a tissue and more precisely, in a cell-specific manner via the alternative use of various promoters located in the first exon. Nevertheless, there is little information concerning the regulation of the testicular aromatase especially in germ cells. This prompted us to… CONTINUE READING
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