The promises and challenges of fusion constructs in protein biochemistry and enzymology

@article{Yang2016ThePA,
  title={The promises and challenges of fusion constructs in protein biochemistry and enzymology},
  author={Haiquan Yang and Long Liu and Fei Xu},
  journal={Applied Microbiology and Biotechnology},
  year={2016},
  volume={100},
  pages={8273-8281}
}
Fusion constructs are used to improve the properties of or impart novel functionality to proteins for biotechnological applications. The biochemical characteristics of enzymes or functional proteins optimized by fusion include catalytic efficiency, stability, activity, expression, secretion, and solubility. In this review, we summarize the parameters of enzymes or functional proteins that can be modified by fusion constructs. For each parameter, fusion strategies and molecular partners are… Expand
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