The promise of minocycline in neurology.

  title={The promise of minocycline in neurology.},
  author={V. Wee Yong and Jennifer Wells and Fabrizio Giuliani and Steven Casha and Christopher Power and Luanne M. Metz},
  journal={The Lancet. Neurology},
  volume={3 12},
The capacity of minocycline to alleviate disease for several neurological disorders in animals is increasingly being recognised. Indeed, that one drug alone can attenuate the severity of disease in stroke, multiple sclerosis, spinal-cord injury, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis is astounding. In this review, we describe the evidence for the efficacy of minocycline in several animal models of neurological disease, discuss the mechanisms by which… CONTINUE READING