The promise and reality of pharmacogenetics in psychiatry.

  title={The promise and reality of pharmacogenetics in psychiatry.},
  author={Peter P. Zandi and Jennifer Toolan Judy},
  journal={Clinics in laboratory medicine},
  volume={30 4},
Existing psychotropic medications for the treatment of mental illnesses, including antidepressants, mood stabilizers, and antipsychotics, are clinically suboptimal. They are effective in only a subset of patients or produce partial responses, and they are often associated with debilitating side effects that discourage adherence. There is growing enthusiasm in the promise of pharmacogenetics to personalize the use of these treatments to maximize their efficacy and tolerability; however, there is… CONTINUE READING


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